Real Peptides PE-22-28
SKU: PEP-4186
$54.99
In stock
PE22-28 is a synthetic seven-amino acid peptide corresponding to residues 22 to 28 of spadin, a fragment released from the propeptide of sortilin (neurotensin receptor 3). It has been characterized in
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Description
PE22-28 is a synthetic seven-amino acid peptide corresponding to residues 22 to 28 of spadin, a fragment released from the propeptide of sortilin (neurotensin receptor 3). It has been characterized in preclinical research as a selective TREK-1 potassium channel blocker, making it a useful tool compound for isolating channel-mediated neuronal signaling endpoints in experimental designs.
PE22-28 has been used in preclinical in vitro and rodent model studies to investigate TREK-1 channel inhibition, hippocampal neurogenesis, synaptic plasticity, and rodent behavioral assay endpoints. Its shortened sequence and higher channel affinity relative to spadin support mechanistic characterization of two-pore potassium channel biology in cell-based and rodent research.
Intended use: In vitro and preclinical in vivo laboratory research only. Not approved for human or veterinary use.
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Research information
For research use only. Not for human consumption.
Research use only
All products listed on this website are supplied strictly for laboratory and scientific research purposes. They are not drugs, foods, cosmetics or medical devices, and are not intended for human or veterinary consumption, diagnosis, treatment or any in-vivo application. Purchasers are responsible for confirming that their intended use complies with all applicable laws and institutional policies.
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